Preheat your oven to 350°F (175°C). Grease a 9x5-inch loaf pan with non-stick spray or butter and flour.
In a medium bowl, whisk together the flour, baking soda, cinnamon, nutmeg, ginger, and salt.
In a separate large bowl, mix the granulated sugar, brown sugar, and eggs until well combined. Add the pumpkin purée, oil, orange juice, and vanilla extract, and mix until smooth.
Gradually add the dry ingredients to the wet ingredients, mixing just until combined. Be careful not to overmix.
Pour the batter into the prepared loaf pan and smooth the top.
Bake for 55–65 minutes, or until a toothpick inserted into the center comes out clean.
Let the bread cool in the pan for about 10 minutes before transferring it to a wire rack to cool completely.